Renee;Your customers problem is a real mystery. I have DEP enabled on my computer and I'm using XP with Service pack 2. This has never been an issue before.
Make sure your customer has enabled all "scripting" in her Internet Explorer -- see Tools menu \ Internet Options \ Security (tab) \ Custom Level \ Scripting category
If the problem persists and is related to DEP alone you might get her to make an adjustment to her DEP settings.
See Control Panel \ System \ Advanced (tab) \ Performance ("Settings" button ) \ Data Execution Prevention (tab) \
Then enable "Turn on DEP for all programs and services except those I select" and have her "Add" your eBook as a program that DEP will allow to run.
Ron